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Thread: Wipe out a single memory - news

  1. #1
    Whats it to ya? Finch's Avatar
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    Lightbulb Wipe out a single memory - news

    New finding in neurophysiology - http://www.nature.com/news/2007/0703...070305-17.html

    "A single, specific memory has been wiped from the brains of rats, leaving other recollections intact."

    Ok i know this is very premature speculation- but if they can find a drug that is safe and has a similar effect, think of it. Now that we know it can be done... who knows?
    Prehaps a new weapon to combat trauma or help therapists.
    Of for the conspirests out there, the knowledge that the government has the potential to wipe a memory clean. Possible? Probably not. But look for it to be mentioned by conspirests some time soon! You have been warned… lol

    To find out, they trained rats to fear two different musical tones, by playing them at the same time as giving the rats an electric shock. Then, they gave half the rats a drug known to cause limited amnesia (U0126, which is not approved for use in people), and reminded all the animals, half of which were still under the influence of the drug, of one of their fearful memories by replaying just one of the tones.

    When they tested the rats with both tones a day later, untreated animals were still fearful of both sounds, as if they expected a shock. But those treated with the drug were no longer afraid of the tone they had been reminded of under treatment. The process of re-arousing the rats' memory of being shocked with the one tone while they were drugged had wiped out that memory completely, while leaving their memory of the second tone intact.



    LeDoux's team also confirms the idea that a part of the brain called the amygdala is central to this process - communication between neurons in this part of the brain usually increases when a fearful memory forms, but it decreases in the treated rats. This shows that the fearful memory is actually deleted, rather than simply breaking the link between the memory and a fearful response.
    that makes no logic

  2. #2
    Doing it wrong until I do it right. xvart's Avatar
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    How did they target the specific memory of the tone? Was it what they heard while the drug was in their system or did it just wipe away a small amount of time prior to the drug usage?

    Very interesting none-the-less.

    xvart.
    "The tragedy of life is not that every man loses; but that he almost wins."

    "Quis custodiet ipsos custodes?"

  3. #3
    Whats it to ya? Finch's Avatar
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    How did they target the specific memory of the tone? Was it what they heard while the drug was in their system or did it just wipe away a small amount of time prior to the drug usage?
    The entire study is very likely to be published in the Journal Nature shortly, as that is the publication's online news site. The library has a subscription, i will have to look and will post more details if i find them.

    From what i have interperted from the news article,Im tentative to say it seems it wipes out a period of time prior to the drug usage...
    that makes no logic

  4. #4
    Stay chooned in for more! Clint's Avatar
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    I wouldn't do it. No regrets, that's my motto.

    Well.... Only if I could forget the Tony Danza show.... I think we'd all rather forget that tradgedy.

  5. #5
    Doing it wrong until I do it right. xvart's Avatar
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    I don't think I would remove anything from my memory. I agree, no regrets; however, there are some times that I wish I could erase a couple stupid things I said when I was in high school because some things never get dropped, and you really look like a fool for speaking such gibberish after a little more development. Of course, I suppose my friends would still remember and still give me a hard time so maybe I wouldn't erase it after all.

    Quote Originally Posted by JustLikeAPill View Post
    I wouldn't do it. No regrets, that's my motto.

    Well.... Only if I could forget the Tony Danza show.... I think we'd all rather forget that tradgedy.
    Haha! I always loved how they would rail on him on E!'s "The Soup." Hilarious.

    xvart.
    "The tragedy of life is not that every man loses; but that he almost wins."

    "Quis custodiet ipsos custodes?"

  6. #6
    Let's positive thinking! seedjar's Avatar
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    It says there in the article that it was the activation of the memory while under the influence of the drug that supposedly reset the memory. 'Wiping' the memory seems kind of imprecise at this point; it seems more like this drug allowed them to overwrite the old bad memory with a neutral one.
    ~Joe
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    I got little tiny bug feet / I don't really know what bugs eat /
    Don't want no one steppin' on me / Now I'm sympathizin' with fleas /
    Livin' like a bug ain't easy / Livin' like a bug ain't easy... o//~

  7. #7
    Whats it to ya? Finch's Avatar
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    seedjar read again
    This shows that the fearful memory is actually deleted, rather than simply breaking the link between the memory and a fearful response.
    Deleted=wiped. there is nothing that says the thing was replaced by some new neutral memory.
    that makes no logic

  8. #8
    Let's positive thinking! seedjar's Avatar
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    That is what it says, but you're also quoting secondary literature. The brain isn't a hard drive - deleted is really a misnomer. It says that the treated rats had decreased activity across the amygdala. Decreased communication between across some general brain organ doesn't necessarily mean something was deleted; it hardly even fits a general definition of the word 'delete.' If you sedated the mouse you'd probably see a similar decrease in brain activity, and probably less anxiety at the threatening tones, too.
    Besides, given that we don't actually know how or specifically where memories are stored, it's difficult to say whether or not this technique removes them. From a cognative science perspective you might say the memory has been wiped, because the behavioral feature associated with that memory is no longer present. But, we can't ask the mouse whether or not it remembers hearing that tone and getting shocked, so it's hard to say it's really gone. Besides, as you say, there's nothing to say that the memory was replaced, so how are we to know that the mouse isn't just regarding the memory of the shock in a different manner?
    ~Joe
    o//~ Livin' like a bug ain't easy / My old clothes don't seem to fit me /
    I got little tiny bug feet / I don't really know what bugs eat /
    Don't want no one steppin' on me / Now I'm sympathizin' with fleas /
    Livin' like a bug ain't easy / Livin' like a bug ain't easy... o//~

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