The main life cycle of these mites are eggs, larva, nymph, and adult. The larval mites feed on the skin cells, but not blood, of animals, including humans. The six-legged parasitic larva feeds on a large variety of creatures including humans, rabbits, toads, box turtles, quail, and even some insects. After crawling onto their host, they inject digestive enzymes into the skin that break down skin cells. They do not actually "bite," but instead form a hole in the skin called a stylostome and chew up tiny parts of the inner skin, thus causing severe irritation and swelling. The severe itching is accompanied by red pimple-like bumps (papules) or hives and skin rash or lesions on a sun-exposed area. For humans, itching usually occurs after the larvae detach from the skin.
After feeding on their hosts, the larvae drop to the ground and become nymphs, then mature into adults which have 8 legs and are harmless to humans. In the post larval stage, they are not parasitic and feed on plant materials. The females lay 3–8 eggs in a litter, usually on a leaf or under the roots of a plant, and die by autumn.